Location: The Francis Crick Institute, Midland Road, London

Salary: From £47,080 with benefits, subject to skills and experience)

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

The Research Group

The Cader lab utilises state-of-the-art techniques to study the metabolism of immune cells such as macrophages and dendritic cells. We seek to understand how metabolic dysfunction in these cells can predispose to conditions such as Inflammatory Bowel Disease (IBD) or Rheumatoid Arthritis.

We are also interested in identifying the metabolites our cells are exposed to from the environment (such as those from our diet or microbiota).

https://www.crick.ac.uk/research/labs/zaeem-cader

About the role

We are seeking an enthusiastic, hard-working and conscientious senior laboratory research scientist to join our new research team.

This position would be ideal for post-doctoral candidates with an interest and expertise in metabolism and/or immunology as well as animal experimentation.

You should already have extensive experience in mammalian cell culture, in vivo (mouse) experimentation and cell/molecular biology. You should also have familiarity and expertise across multiple immunology and/or metabolomic relevant techniques.

What you will be doing

You will:

• Undertaking own research project and independently designing and performing experiments to study immune responses and cell metabolism
• Mouse colony management and independently conducting in-vivo experiments
• Scientific and technical support for group members, such as tissue harvesting, primary cell isolation and sample processing
• Data management and analysis
• Training and supervision of students
• Lab management including organising lab space, attending quadrant meetings, ordering consumables and grant management

Please see full job description here

About you

You will have

• PhD or equivalent experience in metabolism and/or immunology or other relevant discipline*
• Expertise in several relevant molecular or cell biology techniques such as mammalian tissue culture and/or PCR, cloning, western blotting, transfection etc
• Experience in primary cell isolation, tissue harvest and sample preparation/processing for analyses such as transcriptomics, metabolomics, microscopy, flow cytometry*
• Current or previous animal licence holder (PIL or non-UK equivalent) with significant experience in performing mice experiments and willing to undergo additional training as required*
• Extensive experience in either immune assays e.g. cytokine production or studying metabolism e.g. metabolomics, extracellular flux assays etc*

*Minimum Criteria

About Working at the Crick… 

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact karen.au@crick.ac.uk 

To read more about our EDI approach, click here.  

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

Please apply via the ‘Apply’ button above.